Bone defect is a common disease in orthopedics and maxillofacial surgery, which is caused by trauma, infection and tumor resection. Broke through new Gao Jiangren porous titanium alloy structure of the subject design, precise preparation technology, and combining the titanium alloy material manufacturing technology, electron beam in situ preparation of barium titanate piezoelectric ceramic surface treatment technology and ultrasonic treatment in vitro technology, developed a porous titanium alloy artificial bone material that could satisfy the requirement of bone tissue repair.
At present, the porous titanium alloy artificial bone material developed in this project has passed the biocompatibility test. The research and development of intervertebral fusion and femoral head support rods porous structure of orthopedic products such as finished animal experiment evaluation, compared with control group, significantly improve the efficiency of defect bone tissue repair (20% or higher); Two products, acetabular cup and perforated intervertebral fusion device, which mimic the surface structure of bone trabecular, have passed the registration test of the state food and drug administration and entered the clinical trial study.
Bone repairing biomaterials are the research direction supported by biomedical materials. The successful development of new high strength and toughness porous titanium alloy artificial bone repair materials has laid a solid foundation for the development of China's own intellectual property rights of bone repair biological materials and related equipment industry.
