Tantalum coated multi-porous polyetheretherketone artificial bone scaffold is 3D printing manufacturing method. Firstly, CT scans the bone tissue at the injured part of human body, and the bone tissue at the missing part can scan the tissue structure at the symmetrical part, obtain the image data of the injured bone and import it into Mimics software to establish the 3D bone model of the specified part of human body. Generate motion track code through 3D printing system control software; The 3D printing system was used to print the polyether ether ketone artificial bone scaffold until the entire manufacturing process of the artificial bone scaffold was completed. The dried artificial bone scaffold was placed into the sputtering chamber of the magnetron sputtering instrument, and then glued to the loading platform with silver adhesive. Tantalum coating was applied to the artificial bone scaffold by magnetron sputtering technology. After the tantalum coating was completed, the sputtering chamber was deflated, the artificial bone scaffold was taken out, and the tantalum coated multi-porous polyether ether ketone scaffold was disinfected and all steps were completed. The invention makes an artificial bone scaffold by 3D printing, making the scaffold harmless to human body.
Bone is the scaffold of the human body, responsible for supporting, protecting, bearing, hematopoietic, calcium storage and other functions, is an important organization of the human body.
Clinically, bone defects are often caused by trauma, infection, congenital defects and other reasons, which are the treatment problems faced by orthopedics every day. It is an ideal way to make artificial bones with artificial materials to fill the bone defects. Artificial bone is a substitute for human bone made of artificial materials. The ideal artificial bone should have good bone conduction, bone induction and bone formation. With the deepening of research on artificial bone, the function of artificial bone is not only to replace bone defects, but more to imitate the complex heterogeneous porous structure of human bone, thus increasing the bioactive surface area of artificial bone, so as to enhance the adhesion of osteoblasts and ensure the reliable long-term association with human bone. In order to improve the contact area between artificial bone and osteoblast, most of the existing artificial bones use porous scaffolds. The trabecular metal produced by Zimmer Company in the United States is a good example of this. However, in the existing porous scaffold structure of artificial bone, the pore structure of the scaffold is single, the pore size is fixed, and the pore of the scaffold is difficult to be completely connected, which leads to the great difference between the prepared artificial bone scaffold and human bone, poor biocompatibility, low biological activity, and difficult adhesion of osteoblasts. There are many typical manufacturing methods of artificial bone scaffolds: fiber bonding technology, particle leaching technology, gas foaming technology, phase separation technology. These methods all have certain defects.
